Methylation Pathway Report

What is the Methylation Pathway Report?

Your Methylation Pathway Report shows how your genes may impact your body’s ability to carry out methylation — a vital process that affects everything from energy production and detoxification to mood, brain health, and cardiovascular function.

This report connects your DNA with the key steps of the methylation cycle, showing you where things may be working optimally and where support might be needed.

How It Works

• DNA-based insights: We analyze specific variants (SNPs) in genes involved in methylation, like MTHFR, MTR, MTRR, COMT, and others.
• Pathway visualization: Your results are mapped onto the methylation cycle, so you can see how each gene fits into the process.
• Personalized recommendations: Based on your results, the report provides diet, supplement, and lifestyle suggestions that may help support methylation.
• Lab guidance: It also lists lab markers (such as homocysteine, B12, folate, glutathione) that you can test to confirm how your methylation is functioning in real time.

Key Sections of the Report

1. Results Overview – A snapshot of how your genes may influence overall methylation ability.
2. Gene & SNP Breakdown – Each relevant gene is explained in plain language, with your personal genotype, what it means, and possible health effects.
3. Recommendations – Targeted nutrition and lifestyle steps tailored to your genetic profile.
4. Lab Markers to Check – Optional blood tests you can run with your doctor to see how methylation is showing up in your body.

Common Questions

❓ What is methylation?

Methylation is a chemical process where your body “tags” molecules with methyl groups. It helps regulate DNA, hormones, neurotransmitters, and detox pathways.

❓ What if I have the MTHFR variant?

Variants in MTHFR can affect how efficiently your body converts folate into its active form. Your report explains whether your results suggest reduced activity, and offers targeted support options.

❓ Can I improve methylation if I have gene variants?

Yes. Genes aren’t destiny — your report includes actionable steps such as optimizing folate, B12, choline, and lifestyle factors that can support methylation even if you carry less optimal variants.

❓ How does this report differ from my other SelfDecode reports?

Unlike single-topic reports, the pathway reports (Methylation, Detox, Histamine) map your results onto a whole biochemical cycle. This makes it easier to see how multiple genes interact in a bigger picture.

Next Steps

• Review your Results Overview to see your general predisposition.
• Explore the Gene-SNP Breakdown for details on each variant.
• Check the Recommendations section for targeted support strategies.
• Work with a healthcare professional if you’d like to run the suggested lab markers and personalize your approach further.

By combining your genetic data with practical steps, the Methylation Pathway Report gives you a clear, actionable entry point into supporting one of your body’s most important processes.