What is quality of evidence?

The Quality of Evidence score shows you how much scientific research supports each health report, so you can see which insights are backed by the strongest science. You can filter reports by this score on the Health Reports page.

Understanding the Quality of Evidence score

The Quality of Evidence score rates the scientific strength of each genetic model on a scale of 0 to 5. A higher score means more robust research supports that finding.

The scoring scale

Score 0: Preliminary or questionable data
The genetic model is based on incomplete or uncertain data and may not reflect actual genetic predispositions. We recommend approaching it cautiously and not making health decisions based on it alone.
Score 1: Minimal scientific support
The genetic model lacks substantial evidence and has very little chance of being accurate. More research is needed before drawing conclusions.
Score 2: Low-quality evidence
There is limited scientific support for this model, so it has a low probability of reflecting actual genetic predispositions. Additional research would strengthen confidence in this finding.
Score 3: Moderate-quality evidence
There is moderate scientific support, meaning the finding has an average chance of being accurate. Keep an eye out for future research improvements.
Score 4: High-quality evidence
Strong research supports this genetic model, giving it a good chance of being accurate. Additional validation data would increase confidence even further.
Score 5: Very high-quality evidence
This finding has high-quality research support and has been validated by additional studies. It has a high probability of reflecting actual genetic predispositions.

How we evaluate evidence quality

We assess each genetic model by looking at:

  • Sample size and number of cases in studies
  • Study design and potential confounding factors
  • Participant ethnicity and diversity
  • Number of genetic variants available
  • Statistical strength and model quality metrics

The Quality of Evidence score is a valuable guide, but consider it alongside other factors and talk with a healthcare professional about your health decisions. We're committed to giving you reliable, science-backed information to support your health journey.


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