SelfDecode Whole Genome Sequencing (WGS) FAQ

Whole Genome Sequencing (WGS) is SelfDecode's most advanced genetic analysis option. Unlike standard genotyping, WGS reads your entire genome, unlocking deeper insights including rare variants that can significantly impact your health.

What's Included

WGS Bundles

Our advanced WGS bundles are available at selfdecode.com/en/whole-genome-sequencing-wgs/#get-started and include:

• ACMG-Based Predisposition Report — Screens for clinically significant genetic variants based on the American College of Medical Genetics (ACMG) guidelines. View a sample report (PDF)
• Advanced Pharmacogenomics (PGx) Report — Understand how your genes affect your response to medications
• Rare Variants Advanced Report — Identifies rare genetic variants that may significantly increase your risk for certain conditions
• Premium Subscription — Full access to SelfDecode's personalized health reports and tools
• Decody AI Assistant (3 months included) — Our AI-powered health assistant that uses your genetic data to provide personalized guidance

Already have a SelfDecode DNA kit? You may be eligible for upgrade pricing. Contact our support team for current pricing details.

How It Works

1. Order your WGS kit from our WGS page
2. Receive your kit — Shipping typically takes 10–15 business days
3. Collect your sample using the included swab and mail it back using the provided return materials
4. Lab processing — Once your sample arrives at the lab, processing takes 10–20 business days
5. Access your reports — Your results will appear automatically in your SelfDecode account

Available Reports

Available Now

• ACMG-Based Predisposition Report — Screens for clinically actionable genetic variants recommended by ACMG guidelines
• Rare Variant Analysis — Identifies rare variants with significant health implications

Coming Soon

• Updated disease risk reports — Existing reports (such as Coronary Artery Disease) will be enhanced with rare variant data and updated total genomic risk scores
• Expanded PGx report — A comprehensive pharmacogenomics report covering approximately 800 medications

Frequently Asked Questions

Who is WGS available to?

WGS is currently available to customers in the United States. We are working on expanding availability to additional countries in the future. If you're outside the United States, email support@selfdecode.com for guidance.

I already have a SelfDecode DNA kit. Can I upgrade to WGS?

Yes! Existing customers with a DNA kit can upgrade to WGS. Contact our support team and we'll walk you through your upgrade options and pricing.

How long does it take to get my results?

There are two stages: kit shipping takes approximately 10–15 business days, and lab processing takes 10–20 business days after your sample is received. Total time from order to results is typically 4–6 weeks.

Can I upload my own WGS file from another provider?

No. WGS reports require data processed through our own pipeline. We run the full analysis from raw sequencing data (FASTQ files) through to annotations, which ensures accuracy and consistency. Third-party files (including VCF files) cannot be uploaded.

What is included in the advanced WGS bundles?

The premium bundle includes the ACMG-Based Predisposition Report, Advanced Pharmacogenomics (PGx) Report, Rare Variants Advanced Report, a Premium Subscription, and 3 months of Decody AI Assistant access.

What is Decody?

Decody is our AI-powered health assistant that uses your complete genetic data to give you personalized health insights and recommendations. It's included for 3 months with WGS purchases, and available afterward for additional details. Please visit selfdecode.com or contact us for current pricing.

I live outside the United States. Can I order WGS?

WGS is currently only available for US customers. If you've placed an order from outside the US, our support team will reach out to discuss your options on a case-by-case basis.

Why was my WGS order canceled or refunded?

If your order was canceled, it's likely because WGS is currently restricted to US customers. Our support team will contact you to explain your options.

What makes WGS different from standard genotyping?

Standard genotyping reads specific genetic markers (typically around 700,000). Whole Genome Sequencing reads your entire genome — over 6 billion data points — including rare variants that genotyping chips miss entirely. This provides a much more complete picture of your genetic health risks and traits.

Where can I see a sample report?

You can view a sample ACMG-Based Predisposition Report here: Sample Report (PDF)