Does SelfDecode test APOE?

One gene that has received a lot of attention in recent years is APOE. This guide explains what APOE is, why it matters, and how SelfDecode helps you explore your APOE status.

What is APOE?

APOE (Apolipoprotein E) is a gene that encodes a protein responsible for carrying lipids (fats) in the bloodstream. It plays a key role in cholesterol transport and lipid metabolism.

APOE exists in several different forms, called alleles. The most common are:

APOE ε2
APOE ε3
APOE ε4

Each allele can influence lipid levels and your risk for certain health conditions.

Why is APOE Important?

APOE is especially important because of its connection to:

Cardiovascular health – lipid transport and cholesterol balance
Neurodegenerative diseases – including Alzheimer's risk

It’s important to note that carrying a high-risk APOE variant does not guarantee disease, and people without risk variants can still develop these conditions. Risk is influenced by a combination of genetics, lifestyle, and environmental factors.

APOE Testing with SelfDecode

Yes, we analyze APOE variants.
SelfDecode provides insights into your APOE genotype and associated risks.
This is part of our Gene Reports, which are included in the Essential, Essential+ and Ultimate Bundles.

It's important to work with your doctor to better understand your risks. Our reports do not diagnose or treat any health condition. They are not a substitute for medical advice. If you're diagnosed with a certain health condition, follow your doctor's advice.

How to Access Your APOE Report

Visit your Gene Reports (DNA Functional > Gene Reports) in your SelfDecode account.
Explore your APOE Gene Page or use the Search Feature to learn more.

Learn More About APOE

For in-depth insights, check out our podcast: The Joe Cohen Show, including a brief episode on APOE:

Apple Podcast
Spotify
See your APOE SNP table and learn more here: https://selfdecode.com/app/gene/APOE

Important Notes
SelfDecode reports do not diagnose or treat conditions. Always follow your doctor’s advice.
Scores and gauges reflect the latest science, but models improve over time.
Genetics is only part of the story — lifestyle and environment are also critical.
Risk can vary between ethnic groups depending on the studies included in each report.

Pricing, available reports, features, and bundles may change over time. The offers and bundles displayed on the SelfDecode website always supersede any information in this article. For the most accurate and up-to-date details, please refer to the current offers shown on our website or in your SelfDecode account.

Does SelfDecode test for Alzheimer's Disease risk?

Yes—please see this article for more information about our Alzheimer's Disease Medical Report.

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