Does SelfDecode test APOE?

Yes, SelfDecode analyzes APOE variants as part of your genetic testing. You have access to a dedicated APOE report, an Alzheimer's report, and additional related reports — all findable from your Report Overview Page.

What is APOE?

APOE (Apolipoprotein E) is a gene that produces a protein responsible for carrying lipids in the bloodstream. It plays a key role in cholesterol transport and lipid metabolism.

APOE comes in several forms called alleles — ε2, ε3, and ε4 — each of which can influence lipid levels and your risk for certain health conditions, particularly cardiovascular health and neurodegenerative diseases like Alzheimer's.

Carrying a high-risk APOE variant does not guarantee disease. Risk is shaped by a combination of genetics, lifestyle, and environmental factors.

How to find your reports

All APOE-related reports are available in your SelfDecode account:

1. Go to your Report Overview Page.
2. Search the report name to go directly to it — for example, search "APOE" or "Alzheimer's"

APOE Report

The APOE report provides insights into your APOE genotype, associated risks, and what your results may mean for your health. You can also explore your APOE Gene Page to see your full SNP table and variant details.

Alzheimer's Report

The Alzheimer's report covers genetic risk factors associated with Alzheimer's disease, including APOE variants. Search "Alzheimer's" on your Report Overview Page to access it.

Learn More About APOE

For in-depth insights, check out The Joe Cohen Show podcast:

• Apple Podcasts
• Spotify
• See your APOE SNP table and learn more at https://selfdecode.com/app/gene/APOE

Important Notes

• SelfDecode reports do not diagnose or treat conditions. Always follow your doctor's advice.
• Scores and assessments reflect the latest science, but models improve over time.
• Genetics is only part of the story — lifestyle and environment are also critical.
• Risk can vary between ethnic groups depending on the studies included in each report.

Pricing, available reports, features, and bundles may change over time. The offers and bundles displayed on the SelfDecode website always supersede any information in this article. For the most accurate and up-to-date details, please refer to the current offers shown on our website or in your SelfDecode account.

Looking for help with your results?

SelfDecode has two AI options to help you explore your health data:

• DecodyGPT — our built-in AI health coach, available directly in your account
• Connect via MCP integration — link your SelfDecode data to ChatGPT or Claude for AI-powered insights using your own account

Want more from your SelfDecode plan?

The Ultimate Bundle includes all of our current premium reports in one package:

• Ancestry Report
• Condition Reports
• Longevity Screener
• Medication Check (PGx) Report
• Carrier Status
• Pathway Reports (Methylation, Detox, Histamine & more!)

Upgrade from your dashboard or email support@selfdecode.com with questions.