ChatGPT & Claude Prompt Guide

This guide shows you how to write effective prompts when using SelfDecode's AI integration with ChatGPT or Claude, so you get accurate, personalized answers based on your own results every time. New to the integration? Learn how to set it up here.

Three rules for great prompts

1. Connect your account first. Make sure your SelfDecode account is connected before you start prompting.

• ChatGPT
• Claude

2. Start with "According to my SelfDecode results..." Opening your prompt this way tells Claude or ChatGPT to pull from your connected SelfDecode data instead of answering from general knowledge.

✅ "According to my SelfDecode results, what should my top 3 health priorities be?"

❌ "What should my top 3 health priorities be?"

3. Reference the source of information. Tell Claude or ChatGPT which report, lab data, or lifestyle data to pull from. Vague prompts (like "based on my genetics") can lead to arbitrary results.

✅ "…using my Cardiovascular Health Summary Report…"

❌ "…based on my genetics…"

✅ "…using my relevant lab markers and lifestyle data…"

❌ "…based on my health…"

Tip: For reliable, predictable responses, reference a specific report (for example, your Gut Health Summary Report). For a more exploratory answer with extra insights, reference a health area instead (for example, "gut health genetics").

The prompt formula

A simple structure that works for almost any request:

According to my SelfDecode results, specifically my [source of information], [your specific request].

Example: "According to my SelfDecode results, specifically my Mood & Mental Health Report and my relevant lab markers, give me my top 10 supplement recommendations, and for each one, explain which results are driving the recommendation and why the supplement helps."

Start small, then expand

Complex, multi-part requests reduce accuracy. Break big questions into focused ones instead.

Instead of:

❌ "Considering my whole health picture, give me a full plan with supplements, diet, lifestyle, labs, fitness, and mental health."

Try a sequence:

1. "Based on my Health Overview Report, what are my top 5 supplement, dietary, and lifestyle recommendations, and why?"
2. "Based on my Medication Check (PGx) Report, which medications may require caution?"
3. "Based on my Longevity Screener, which chronic conditions am I at higher risk for, and what lifestyle changes should I focus on?"

Prompt ideas — getting started

Top supplement recommendations: "According to my SelfDecode results, specifically my [Cardiovascular Health Summary / mental health genetics / gut health lab markers / lifestyle factors], give me my top 10 supplement recommendations, and for each one, explain why it works especially well for me."

Diet plan: "According to my SelfDecode results, specifically my genetic results in the Diet & Nutrition Report and my Diet questionnaire, draft a 2-week personalized diet plan."

Lifestyle action plan: "According to my SelfDecode results, specifically my [Fitness Summary Report / weight control genetics / most important lab results], create a detailed one-month lifestyle and workout plan."

Cardiovascular risk summary: "According to my SelfDecode results, specifically my Cardiovascular Health Summary, summarize my key genetic cardiovascular risks and suggest an action plan that prioritizes the highest-risk areas."

Prioritize by importance: "According to my SelfDecode results, specifically my [Health Overview Report / Gut Health Summary / lifestyle assessments], list my 5 most important risks, and suggest my top 5 supplement and lifestyle recommendations."

Prompt ideas — going deeper

Medication and gene interactions to discuss with your doctor: "According to my SelfDecode results, I've been prescribed metformin and a low-dose SSRI. Based on my Medication Check (PGx) Report and metabolic genetics, what interaction risks, metabolizer status, or nutrient depletions should I bring up with my doctor or pharmacist?"

Fatigue and burnout root-cause exploration: "According to my SelfDecode results, I've been dealing with chronic fatigue, poor sleep, and low motivation. Using my genetics, labs, and lifestyle data, identify the most likely root causes and build a prioritized recovery plan I can review with my provider."

Pre-conception nutrition: "According to my SelfDecode results, I'm planning to conceive in the next 6 months. Based on my nutrigenetics — especially methylation, folate metabolism, and inflammation markers — design a targeted pre-conception supplement and diet plan I can confirm with my OB or provider."

Post-illness / long-haul recovery: "According to my SelfDecode results, I've had brain fog, fatigue, and gut issues for 4 months after an illness. Based on my genetic predispositions for inflammation, oxidative stress, and immune regulation, suggest a personalized recovery plan."

Cardiovascular risk and lifestyle: "According to my SelfDecode results, I have a family history of heart disease. Based on my lipid metabolism genetics, inflammation markers, and current lifestyle, what are my highest-priority modifiable risks, and which specific dietary and supplement changes are best matched to my genotype?"

Common mistakes to avoid

Do even more from your AI chatbot

You can now generate and download PDF reports, buy new reports, upload labs, and answer lifestyle questions — all directly from your AI integration.

Want to keep everything in-house?

AI Hyperintelligence is SelfDecode's own built-in AI. It runs entirely inside the platform, so your data never leaves SelfDecode and no third-party app or account is required.

Learn how to use AI Hyperintelligence.

Questions & feedback

To submit feedback, use the built-in feedback tool — reference SelfDecode and say you're submitting feedback. You'll receive a confirmation once it's gone through.

Found a prompt that works really well? Share it with us at support@selfdecode.com.